Publications of the Students

Vedelek, B., Kovács, Á., Boros, I. M. (2021) Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins. Open Biol. 11:210261.
Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins (nih.gov)

Keller-Pinter, A., Gyulai-Nagy, Sz., Becsky, D., Dux, L., Rovo L. (2021) Syndecan-4 in Tumor Cell Motility. Cancers (Basel) 13:3322.
Syndecan-4 in Tumor Cell Motility (nih.gov)

Tóth, N., Szlovák, J., Kohajda, Zs., Bitay, G., Veress, R., Horváth, B., Papp, J. Gy., Varró, A., Nagy, N. (2021) The development of L-type Ca 2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium. Sci Rep. 11:16652.
The development of L-type Ca2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium (nih.gov)

Horváth, M., Nagy, G., Zsindely, N., Bodai, L., Horváth, P., Vágvölgyi, Cs., Nosanchuk, J. D., Tóth, R., Gácser, A. (2021) Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation. mSystems. 6:e00163-21.
Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation (nih.gov)

Iacone, Y., Morais, T. P., David, F., Delicata F, Sandle, J., Raffai, T., Parri, H. R., Weisser J. J., Bundgaard, C., Klewe, I, V., Tamás, G., Thomsen, M. S., Crunelli, V., Lőrincz, M. L. (2021) Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures. Epilepsia. 62:1729-1743.
Systemic administration of ivabradine, a hyperpolarization‐activated cyclic nucleotide‐gated channel inhibitor, blocks spontaneous absence seizures - Iacone - 2021 - Epilepsia - Wiley Online Library

Szikora, Sz., Görög, P., Kozma, Cs.; Mihály, J. (2021) Drosophila Models Rediscovered with Super-Resolution Microscopy. Cells 10:1924.
Drosophila Models Rediscovered with Super-Resolution Microscopy (nih.gov)

Kozma, M., Mészáros, Á., Nyúl-Tóth, Á., Molnár, K., Costea, L., Hernádi, Zs., Fazakas, Cs., Farkas, E. A., Wilhelm, I., Krizbai, I. A. (2021) Cerebral Pericytes and Endothelial Cells Communicate through Inflammasome-Dependent Signals. Int J Mol Sci. 22:6122.
Cerebral Pericytes and Endothelial Cells Communicate through Inflammasome-Dependent Signals (nih.gov)

Manczinger, M., Koncz,B., Balogh, G.M., Papp, B.T., Asztalos, L., Kemény, L., Papp, B., Pál, C. (2021) Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity. Nat. Cancer 2:950-961.
Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity | Nature Cancer

Bozó, R., Danis, J., Flink, L., B., Vidács, D. L., Kemény, L., Bata-Csörgő, Zs. (2021) Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin. Life (Basel). 11:599.
Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin (nih.gov)

Vidács, D. L., Veréb, Z., Bozó, R., Flink, L. B., Polyánka, H., Németh, I. B., Póliska, S., Papp, B. T., Manczinger, M., Gáspár, R., Mirdamadi, S., Kemény, L., Bata-Csörgő, Zs. (2021) Phenotypic plasticity of melanocytes derived from human adult skin. Pigment Cell Melanoma Res. 10.1111/pcmr.13012.
Phenotypic plasticity of melanocytes derived from human adult skin - Vidács - - Pigment Cell & Melanoma Research - Wiley Online Library

Poles, M. Z., Nászani, A., Gulácsi, L., Czakó, B., Gál, G. K., Glenz, R. J., Dookhun, D., Rutai, A., Tallósy, Sz. P., Szabó, A., Lőrinczi, B., Szatmári, I., Fülöp, F., Vécsei, L., Boros, M., Juhász, L., Kaszaki, J. (2021) Kynurenic acid and its synthetic derivatives protect against sepsisassociated neutrophil extracellular trap formation and brain mitochondrial dysfunction in rats. Frontiers in Immunol. 12: 717157.
Kynurenic Acid and Its Synthetic Derivatives Protect Against Sepsis-Associated Neutrophil Activation and Brain Mitochondrial Dysfunction in Rats (nih.gov)

Becsky, D., Szabo, K., Gyulai-Nagy, Sz., Gajdos,T., Bartos, Zs., Balind, A., Dux, L., Horvath, P., Erdelyi, M., Homolya, L., Keller-Pinter, A. (2020) Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution. Front Cell Dev Biol. 8: 575227.
Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution (nih.gov)

Bársony, A., Vida, N., Gajda, Á., Rutai, A., Mohácsi, Á., Szabó, A., Boros, M., Varga, G., Érces, D. (2020) Methane Exhalation Can Monitor the Microcirculatory Changes of the Intestinal Mucosa in a Large Animal Model of Hemorrhage and Fluid Resuscitation. Front Med (Lausanne) 7: 567260.
Methane Exhalation Can Monitor the Microcirculatory Changes of the Intestinal Mucosa in a Large Animal Model of Hemorrhage and Fluid Resuscitation (nih.gov)

Topal, G.R, Mészáros, M., Porkoláb, G., Szecskó, A., Polgár, T.F, Siklós, L., Deli, M.A, Veszelka,S., Bozkir, A. (2020) ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood-Brain Barrier. Pharmaceutics 13:38.
ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood–Brain Barrier (nih.gov)

Mészáros, Á., Molnár, K., Nógrádi, B, Hernádi, Zs., Nyúl-Tóth, Á., Wilhelm, I., Krizbai, I. A.(2020) Neurovascular Inflammaging in Health and Disease. Cells 9:1614.
Neurovascular Inflammaging in Health and Disease (nih.gov)

Takeuchi, Y., Harangozó, M., Pedraza, L., Földi, T., Kozák, G., Li, Q., Berényi, A. (2020) Closed-loop stimulation of the medial septum terminates epileptic seizures. Brain 144:885-908.
Closed-loop stimulation of the medial septum terminates epileptic seizures | Brain | Oxford Academic (oup.com)

Porkoláb, G., Mészáros, M., Tóth, A., Szecskó, A., Harazin, A., Szegletes, Zs., Ferenc, Gy., Blastyák, A., Mátés, L., Rákhely, G., Deli, M.A., Veszelka, Sz. (2020) Combination of Alanine and Glutathione as Targeting Ligands of Nanoparticles Enhances Cargo Delivery into the Cells of the Neurovascular Unit. Pharmaceutics 12:635.
Combination of Alanine and Glutathione as Targeting Ligands of Nanoparticles Enhances Cargo Delivery into the Cells of the Neurovascular Unit (nih.gov)

Czinege, Gy., Lerner, Z., Magyar, L.B., Soós, B., Tóth, R., Kristó, I., Vilmos, P., Juhász, G., Kovács, A., Hegedűs, Z., Sensen, C., Kurucz, E., Andó, I. (2020) Cellular Immune Response Involving Multinucleated Giant Hemocytes with Two-Step Genome Amplification in the Drosophilid Zaprionus indianus. J Innate Immun 12:257-272.
Cellular Immune Response Involving Multinucleated Giant Hemocytes with Two-Step Genome Amplification in the Drosophilid Zaprionus indianus (nih.gov)

Bálint, A.R., Puskás, T., Menyhárt, Á., Kozák, G., Szenti, I., Kónya, Z., Marek, T., Bari, F., Farkas, E. (2019) Aging impairs cerebromicrovascular reactivity at preserved resting cerebral arteriolar tone in the laboratory rat. Front Aging Neurosci 11:301

Szili, P., Draskovits, G., Révész, T., Bogar, F., Balogh, D., Martinek, T., Daruka, L., Spohn, R., Vásárhelyi, B.M., Czikkely, M., Kintses, B., Grézal, G., Ferenc, Gy., Pál, Cs., Nyerges, Á. (2019) Rapid evolution of reduced susceptibility against a balanced dual-targeting antibiotic through stepping-stone mutations. Antimicrob Agents Chemother 63 pii: e00207-19

Obál, I., Nógrádi, B., Meszlényi, V., Patai, R., Ricken, G., Kovacs, G.G., Tripolszki, K., Széll, M., Siklós, L., Engelhardt, J.I. (2019) Experimental motor neuron disease induced in mice with long-term repeated intraperitoneal injections of serum from ALS patients. Int J Mol Sci 20: 2573.

Tóth, E., Maleth, J., Závogyán, N., Fanczal, J., Grassalkovich, A., Erdős, R., Pallagi, P., Horváth, G., Tretter, L., Bálint, E.R., Rakonczay, Z., Venglovecz, V., Hegyi, P. (2019) Novel mitochondrial transition pore inhibitor N-methyl-4-isoleucine cyclosporin is a new therapeutic option in acute pancreatitis. J Physiol 597: 5879-5898

Szabó, I., M. Tóth, O.; Török, Zs., Varga, D.P., Menyhárt, Á., Frank, R., Hantosi, D., Horváth, I., Bari, F., Vigh, L., Farkas, E. (2019) The impact of dihydropyridine derivatives on the cerebral blood flow response to somatosensory stimulation and spreading depolarization in the intact and ischemic rat cerebral cortex. Br J Pharmacol 176: 1222-1234

Tripolszki, K., Danis, J., Padhi, A.K., Gomes, J., Bozó, R., Nagy, Zs.F., Nagy, D., Klivényi, P., Engelhardt, J.I., Széll, M. (2019) Angiogenin mutations in Hungarian patients with amyotrophic lateral sclerosis: Clinical, genetic, computational, and functional analyses. Brain Behav 9:e01293

Tripolszki, K., Gampawar, P., Schmidt, H., Nagy, Zs.F., Nagy, D., Klivényi, P., Engelhardt, J.I., Széll, M. (2019) Comprehensive genetic anaylsis of a Hungarian amyotrophic lateral sclerosis cohort. Front Genet 10:732

Nászai, A., Terhes, E., Kaszaki, J., Juhasz, L. (2019) Ca(2+)N It Be Measured? Detection of Extramitochondrial Calcium Movement With High-resolution FluoRespirometry. Sci Rep 9: 19229

Cseh, EK., Veres, G., Szentirmai, M., Nánási, N., Szatmári, I., Fülöp, F., Vécsei, L., Zádori, D. (2019) HPLC method for the assessment of tryptophan metabolism utilizing separate internal standard for each detector. Anal Biochem 574: 7-14

Menyhárt Á, Farkas AE, Varga DP, Frank R, Tóth R, Bálint AR, Makra P, Dreier JP, Bari F, Krizbai IA, Farkas E. Large-conductance Ca(2+)-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization. Neurobiol Dis. 2018 Nov;119:41-52.

Varga, G., Ugocsai, M., Hartmann, P., Lajkó, N., Molnár, R., Szűcs, S., Jász, D.K., Érces, D., Ghyczy, M., Tóth, G., Boros, M. (2018) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26: 261-271.

Hartmann, P., Butt, E., Feher, A., Szilagyi, A.L, Jasz, K.D., Balazs, B., Bakonyi, M., Berko, S., Eros, G., Boros, M., Horvath, G., Varga, E., Csanyi, E. (2018) Electroporation-enhanced transdermal diclofenac sodium delivery into the knee joint in a rat model of acute arthritis.joint in a rat model of acute arthritis. Drug Des Devel Ther 12: 1917-1930

Poles MZ, Bódi N, Bagyánszki M, Fekete É, Mészáros AT, Varga G, Szűcs S, Nászai A, Kiss L, Kozlov AV, Boros M, Kaszaki J. Reduction of nitrosative stress by methane: Neuroprotection through xanthine oxidoreductase inhibition in a rat model of mesenteric ischemia-reperfusion. Free Radic Biol Med. 2018 May 20;120:160-169.

Mészáros M, Porkoláb G, Kiss L, Pilbat AM, Kóta Z, Kupihár Z, Kéri A, Galbács G, Siklós L, Tóth A, Fülöp L, Csete M, Sipos Á, Hülper P, Sipos P, Páli T, Rákhely G, Szabó-Révész P, Deli MA, Veszelka S. Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier. Eur J Pharm Sci. 2018 Oct 15;123:228-240.

Nánási N, Veres G, Cseh EK, Szentirmai M, Martos D, Sümegi E, Hadady L, Klivényi P, Vécsei L, Zádori D. The detection of age-, gender-, and region-specific changes in mouse brain tocopherol levels via the application of different validated HPLC methods. Neurochem Res. 2018 Nov;43(11):2081-2091.

Manczinger M, Bodnár V, Papp BT, Bolla SB, Szabó K, Balázs B., Csányi E, Szél E, Erős G, Kemény L. Drug Repurposing by Simulating Flow Through Protein–Protein Interaction Networks. Clin Pharmacol Ther. 2018 Mar; 103(3):511-520.

Patai R, Nógrádi B, Engelhardt JI, Siklós L. Calcium in the pathomechanism of amyotrophic lateral sclerosis - Taking center stage? Biochem Biophys Res Commun. 2017;483:1031-1039.

Patai R, Nógrádi B, Meszlényi V, Obál I, Engelhardt JI, Siklós L. Az amyotrophiás lateralsclerosis patofiziológiai tényezőinek központi kapcsolóeleme, a kalcium. Ideggyogy Sz 2017;70:247–257.

Meszlényi V., Patai R., Nógrádi B., Engelhardt J.I., Siklós L. Commentary: Calcium in the pathomechanism of amyotrophic lateral sclerosis – Taking center stage? J. Neurol. Neuromed. 2017; 2(4): 1–4.

Menyhárt Á, Zölei-Szénási D, Puskás T, Makra P, Orsolya MT, Szepes BÉ, Tóth R, Ivánkovits-Kiss O, Obrenovitch TP, Bari F, Farkas E. Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain. Sci Rep. 2017;7:1154.

Veres, G., Fejes-Szabó, A., Zádori, D., Nagy-Grócz, G., László, AM., Bajtai, A., Mándity, I., Szentirmai, M., Bohár, Z., Laborc, K., Szatméri, I., Fülöp, F., Vécsei, L., Párdutz, Á. (2016) A comparative assessment of two kynurenic acid analogs in the formalin model of trigeminal activation: a behavioral, immunohistochemical and pharmacokinetic study. J Neural Transm 124: 99-112

Veszelka, Sz., Bocsik, A., Walter, F.R., Hantosi, D., Deli, M.A. (2015) Blood-brain barrier co-culture models to study nanoparticle penetration: focus on co-culture systems. Acta Biol Szeged 59(Suppl.2):157-168.

Veres, G., Molnár, M., Zádori, D., Szentirmai, M., Szalárdy, L., Török, R., Fazekas, E., Ilisz, I., Vécsei, L., Klivényi, P. (2015) Central nervous system-specific alterations in the tryptophan metabolism in the 3-nitropropionic acid model of Huntington's disease. Pharmacol Biochem Behav 132: 115-124

Fejes-Szabó, A., Bohár, Z., Vámos, E., Nagy-Grócz, G., Tar, L., Veres, G., Zádori, D., Szentirmai, M., Tajti, J., Szatmári, I., Fülöp, F., Toldi,  J., Párdutz, Á., Vécsei, L. Pre-treatment with new kynurenic acid amide dose-dependently prevents the nitroglycerine-induced neuronal activation and sensitization in cervical part of trigemino-cervical complex. J Neural Transm 121: 725-38